Phentermine 37.5 mg
$80.00
Phentermine (37.5mg)
Phentermine is an amphetamine-based drug that helps with weight loss. It is an appetite suppressant that doesn’t help reduce weight alone, but coupled with a good diet and light exercise, it impacts the Central Nervous System (CNS), which in turn, promotes weight loss.
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- Description
Description
What Is Phentermine 37.5mg?
Phentermine is a prescription weight loss medication.
It was approved by the FDA in 1959 for short-term use of up to 12 weeks for people older than 16.
In the 1990s, phentermine was combined with other weight loss drugs. This drug combination was commonly called fen-phen.
After reports of significant heart problems in users, the FDA pulled the other two drugs used in the treatment — fenfluramine and dexfenfluramine — from the market.
Phentermine goes by the brand names Adipex-P, Lomaira, and Suprenza, or you can find it in combination medications for weight loss, such as Qsymia.
It’s a controlled substance due to its chemical similarities to the stimulant amphetamine — making it available only with a prescription.
Your doctor may prescribe phentermine if you’re obese, meaning that your body mass index (BMI) is greater than or equal to 30.
It may also be prescribed if you’re overweight with a BMI greater than or equal to 27 and have at least one weight-related condition, such as high blood pressure, high cholesterol, or type 2 diabetes
How Does It Work?
Phentermine belongs to a class of drugs called “anorectics,” also known as appetite suppressants.
Taking phentermine helps suppress your appetite, thereby limiting how many calories you eat. Over time, this can lead to weight loss.
While the exact mechanisms behind the appetite-reducing effects of phentermine remain unclear, the drug is thought to act by increasing neurotransmitter levels in your brain.
Neurotransmitters are your body’s chemical messengers and include norepinephrine, serotonin, and dopamine.
When your levels of these three chemicals increase, your feeling of hunger decreases.
However, you may build a tolerance to the appetite-suppressing effects of phentermine within a few weeks. In that case, you should not increase your dose of the drug but stop using it altogether.
Effective for Weight Loss
Several clinical studies have proven that phentermine can boost fat loss.
The expected average weight loss with phentermine use is 5% of your initial body weight. Yet, over 12 weeks, it can be as high as 10%. This equates to a weight loss of 10–20 pounds (4.5–9 kg) for a 200 pound (90.7 kg) person.
In a meta-analysis of six studies, people who took the average dose of 27.5 mg of phentermine for 13 weeks lost an average of 13.9 pounds (6.3 kg) compared to 6.2 pounds (2.8 kg) in placebo groups.
While phentermine has been shown to be effective for weight loss, it may work better when combined with topiramate.
Topiramate is a drug that has been used on its own to treat seizures but — like phentermine — also has appetite-reducing properties.
Topiramate and phentermine is a combination medication sold under the brand name Qsymia.
Compared to three other commonly prescribed drugs for weight loss, the combination of phentermine and topiramate was associated with the highest odds of losing at least 5% of the initial body weight.
What’s more, research suggests that the phentermine and topiramate combination is the most effective weight loss medication to date — with people achieving an average weight loss of 21.6 pounds (9.8 kg) after taking the maximum dose for one year.
In users, this weight loss has translated to a significant decrease in waist circumference, improved insulin sensitivity, and blood sugar control, as well as favorable effects on triglyceride and cholesterol levels.
May Be Helpful for Certain Eating Disorders
The combination of phentermine and topiramate may help reduce binge eating in people with binge eating disorder (BED) and bulimia nervosa.
BED is characterized by eating large amounts of food, often quickly and to the point of discomfort. It’s also associated with a feeling of losing control during the binge, as well as feelings of shame or guilt afterward.
Bulimia nervosa involves the same binge-eating behavior as with BED, but includes behaviors, such as self-induced vomiting, in an attempt to compensate for the effects of binge eating.
In a small 12-week study in obese or overweight people with BED, the phentermine and topiramate drug combination was associated with significant reductions in weight, BMI, and binge-eating episode frequency.
In another 12-week study, people with BED or bulimia nervosa were randomized to receive the drug combination or a placebo.
Over 28 days, treatment with the phentermine and topiramate combination decreased the participants’ number of binge-eating days from 16.2 to 4.2. The same results were not observed in the placebo group.
By reducing binging episodes, the drug combination may help the estimated 40–80% of people with BED or bulimia nervosa who are overweight or obese lose weight while improving mood and a sense of control with eating.
Side Effects and Precautions
Phentermine alone is designed for short-term use only, as there are no long-term studies on its safety.
However, the FDA has approved phentermine in combination with topiramate for long-term use, since the dosage of the two ingredients is lower than the maximum doses of the individual drugs.
While serious adverse effects are rare, studies report several side effects of the phentermine and topiramate combination.
The most commonly reported side effects include:
- Dry mouth
- Sleeping problems
- Dizziness
- Heart palpitations
- Flushing of the skin
- Fatigue
- Constipation
- Irritability
You shouldn’t take phentermine if you have heart disease, hyperthyroidism, glaucoma, or if you’re pregnant or nursing.
Phentermine should also not be prescribed in combination with monoamine oxidase inhibitors (MAOIs), a class of medications used to treat depression.
Your doctor will determine whether phentermine is appropriate and safe for you.
Healthy Ways to Promote and Maintain Weight Loss
While phentermine can be a powerful weight loss aid, the only proven way to shed weight — and to keep it off in the long term — is cultivating healthy lifestyle behaviors.
Without making the proper changes, it is likely that you’ll gain back the weight you lost — and possibly more — once you stop taking phentermine.
A comprehensive lifestyle change includes:
- A reduced-calorie diet: If you have excess weight to lose, eat 300–500 fewer calories per day. A registered dietitian can help you tailor this range based on your preferences and goals.
- Prioritize nutrient-dense foods: Nutrient-dense foods — such as fruits and vegetables — are relatively low in calories and high in nutrients, such as fiber, vitamins, and minerals.
- Increase physical activity: Guidelines recommend a minimum of 150 minutes per week of moderate aerobic exercise, such as brisk walking or running.
- Behavioral strategies: Behavior changes includes regular self-monitoring of food intake, physical activity, and your weight, plus making adjustments as needed.
Making these lifestyle changes can be difficult and shouldn’t happen all at once. It will take an investment of your time and energy — but the outcome will be long-term weight loss and overall better health.
Phentermine 37.5 mg carries the risks for side effects just as any other medication but holds significant potential for helping individuals who struggle with obesity.
Side effects of Phentermine 37.5 mg range from mild to severe with the most common of having the possibility to develop:
- sleeplessness or insomnia
- moodiness
- increased energy levels
- nervousness
- irritability
- dry mouth
- and headaches being the mild ones
These side effects usually occur within the first few days of treatment and are believed to get less once the body has been used to Phentermine 37.5 mg.
However, it is advised that the user should be monitored by a physician even if just feeling minor side effect.
Physical side effects can include:
- gastrointestinal upset
- dizziness
- hypertension
- and nausea
Warning: Drug is Not Recommended for Everybody.
Phentermine 37.5 mg’s effectiveness more draws people on giving it a try. But despite its effectiveness, there are several health conditions that do not benefit from using it.
Phentermine 37.5 mg is not appropriate for individuals who have hypertension or cardiovascular disease. Phentermine 37.5 mg is a medication that can cause symptoms associated with mental health problems and underlying mood disorders.
Examples of mental health problems are Bipolar Disorder, Panic Disorder, depression or anxiety. It should also not be taken by individuals with a history of drug addiction or psychosis. Though it is not believed to be addictive, person with history of addiction may develop dependence to the said drug.
Phentermine 37.5 mg should not be taken with some medications including cold medicines, antidepressants and other medications which affect the autonomic nervous system. Those who take this medication should consult their physician and pharmacist to check for possible drug contraindications.
Phentermine 37.5 mg is a medication that is prescribed by the medical community.
Due to the effect that Phentermine 37.5 mg has on the autonomic nervous system and satiety center of the brain, this medication may trigger mental health changes for those with underlying mental health diagnosis such as anxiety, panic disorder, and bipolar disorder. Any individual with a history of these mental health disorders should make his prescribing physician aware of his medical history and use Phentermine 37.5 mg with caution.